You cannot donate if you:

• Are HIV positive
• Have Hepatitis B or Hepatitis C
• Have HTLV infection
• Engage in high-risk sexual behavior that increases infection risk

These exclusions are in place to protect immunocompromised patients receiving transplants.

Individuals with the following conditions are not eligible:

• Inherited blood disorders (e.g., Sickle Cell Disease, Thalassemia, including carriers)
• Bleeding disorders (e.g., Hemophilia, von Willebrand disease)
• Autoimmune diseases such as:
  • Lupus
  • Rheumatoid Arthritis
  • Crohn’s disease

These conditions may affect both donor safety and stem cell quality.

You may be excluded if you have:

• Uncontrolled diabetes
• Epilepsy
• Severe asthma (2+ attacks per year)
• Heart disease or kidney disease
• History of organ transplant
• Any history of cancer
• Neurological conditions such as:
  • Multiple Sclerosis (MS)
  • Parkinson’s disease
• Mental health conditions requiring lithium or multiple antidepressants

Some conditions may only temporarily prevent donation:

• Active tuberculosis (TB) treatment
• Recent infections or ongoing medical treatments
• Temporary health instability

Eligibility may be reassessed once the condition is resolved.

Certain medications can disqualify donors, especially if they cannot be safely paused:

• Blood thinners
• Long-term steroid use
• Antidepressants or anxiety medications
• Any medication that cannot be safely stopped if matched with a patient

Always consult the SABMR registry team before making assumptions about medication eligibility.

If you are ineligible to donate blood, you are generally also ineligible to donate stem cells.

These guidelines ensure:

• Donor safety during the collection process
• The highest chance of successful transplantation
• Reduced risk to patients with weakened immune systems
• Compatibility and quality of stem cells collected